Buerger's disease is also called Thromboarteritis obliterans. It occurs in young males mostly below 40 years. It is common in Israel, South America and India. It is strongly associated with heavy smoking and caffeine. It mostly involves smalls and medium arteries and veins of the extremities.
Pathology:
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Pathology:
- Recurrent neutrophilic vasculitis with micro abscesses.
- Segmental thrombosis- leads to vascular insufficiency.
- Severe pain (claudication) in the affected extremity
- Thrombophlebitis
- Raynaud phenomenon
- Ulceration and gangrene
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